Metachronous Nasopharyngeal Carcinoma in a Case of Carcinoma of the Larynx- A Rare Entity

International Journal of Research in Health Sciences,2,3,898-902.
Published:July 2014
Type:Case Report
Author(s) affiliations:

Kaustuv Das Biswas1, Sirshak Dutta2, Soumya Ghatak3, Arya Sen4, Ramanuj Sinha

1-RMO cum Clinical Tutor, IPGMER & SSKM Hospital, Kolkata, West Bengal, INDIA.

2-RMO cum Clinical Tutor, Calcutta Medical College & Hospital, Kolkata, West Bengal, INDIA.

3-RMO cum Clinical Tutor, R.G.Kar Medical College & Hospital, Kolkata, West Bengal, INDIA. 

4-RMO-cum-clinical-tutor, Dept. of Immune Hematology & Transfusion medicine, Murshidabad Medical College, West Bengal, INDIA.

5-Professor, Department of Otolaryngology, R.G.Kar Medical College & Hospital, Kolkata, West Bengal, INDIA.


Introduction: Second primary tumour (synchronous or metachronous) is increasingly being reported but in most of the cases lung and oral cavity or oropharyngeal carcinomas have been described in association with carcinoma of the larynx. Case report: The occurrence of nasopharyngeal carcinoma as a metachronous second primary in a case of carcinoma of the larynx is very uncommon. This is a rare case of such an association. Conclusion: This case highlights the need of long term follow up of all head & neck malignancy patients. A very high degree of suspicion should be maintained to initiate thorough examination including nasopharyngeal examination either by endoscopy or clinically in order to expedite the diagnosis of second primary.

Contrast enhanced computed tomography scan of nasopharynx, axial section, showing an enhancing growth in left lateral wall of nasopharynx, occluding the fossa of Rosenmuller.